MY HEART DOCTOR
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Mutations
Mutations are changes in the genes or chromosomes of an individual and are inherited to the offspring The factors that cause mutations are called mutagens, while individuals who suspect mutations are called mutants.
Gene Mutation (Point Mutation)
Gene mutations are mutations that occur due to changes in one base pair of DNA of a gene. The types of gene mutations are listed as follows.
Substitution is the exchange or replacement of the nitrogenous bases of DNA with other nitrogenous bases. Substitutions are divided into two types, namely transition (replacement of similar nitrogenous bases) and transversion (replacement of non-similar nitrogenous bases).
Insertion is the addition or insertion of one or more nitrogenous bases into a DNA chain.
Deletion is the reduction of one or more nitrogenous bases that occurs during DNA replication.
Chromosomal Mutation

Chromosomal mutations are mutations that occur due to changes in chromosomes, both the structure of the chromosome and the number of chromosomes.
a. Chromosomal mutations due to changes in chromosome structure called chromosomal aberrations occur due to chromosomal damage.
Deletion is a chromosome mutation that occurs because a chromosome loses part of its locus.Duplication is a chromosome mutation that occurs due to the addition of a chromosome locus.Translocation is a chromosome mutation that occurs due to the exchange of genes from one. chromosomes to other chromosomes that are not homolognya.Inversion is a chromosome mutation that occurs due to changes in the sequence or location of genes on the chromosomes that are twisted, so that gene insertion occurs.
b. Chromosome mutations due to changes in the number of chromosomes are called ploidi, which is a mutation that occurs due to changes in the number of chromosomes.
Euploidy is a chromosomal mutation that occurs due to the addition or reduction in the number of chromosomes, for example haploid, diploid, triploid, and polyploid.
An eneuploid is a chromosome mutation that occurs due to changes in the chromosomes of the individual genome, monosomy, trisomy, and nulisomy. Eneuploid causes several disorders, namely:
Down syndrome (45A + XY), patients have a trisomy chromosome (2n + 1) the addition of the chromosome occurs in the croosome no 21, low IQ, narrow eyes, short legs called mongolism.Turner syndrome, which is a type of, experiencing Y chromosome deficiency (44 + X), occurs in people who are female sex, ovaries do not grow, low IQ, and small body size.Klinefelter syndrome (44A + XXV), and, patients have a trisomy chromosome (2n + 1) suffered in men, testicles do not grow, and the growth of breasts.Super women (44 A + XXX).
Mutations based on the source can be divided into two, namely:
Natural Mutation
Natural mutations or spontaneous mutations are mutations that occur naturally by themselves or the cause is not known with certainty.
Artificial Mutation
Artificial mutations are mutations that occur due to intentional or human intervention, for example the process of making superior seeds.
Various causes of mutations or mutagens.
Biological mutagens, biological materials that can cause mutations, such as viruses and bacteria.
Mutagenphysics, physical materials that can cause mutations, such as temperature, ultraviolet light, X-rays, gamma rays, and radiacosmis.
Chemical mutagens, chemicals that can cause mutations include colchicine, acridine, formaldehyde, ethyl methane sulfate, ethyl ethane sulfanoate, nitric acid, hydrogenperoxide.
The three subjects make students tired because it takes hours, because it turns out that one of the subjects is all practicum.
"Huh tirednya.." said Muthia.
"Yes, he said next week a genetic practicum, uh even today" Selfia said.
"Yes, how else will the lecturer next Sunday on marriage leave" said Mimi.
"Emm, where are we.. Make the saying tired nih.." said Irma.
"Eh we go to the mall aja yok never drink ice cream that" said Selfia.
"Sars.. Tracts yes.." ask Selfia to Saridi by blinking her eyes repeatedly.
"Why eyes? your worms Fi?" saridi.
"Yes worms because of the impromptu practice earlier. Deal with Abang Saridi." said Selfia.
"Jaudah, come on." said Saridi relented.
"Eh, you guys.. Mimi is not." said Mimi.
"Yes Mi, all of you are not tasty if there is less. Denis.
"Emm but want to go to Mimk cosan first, Mimi wants to take this first." said Mimi by pointing to the place of the cake.
"What the hell didn't make Mimi" Denis said.
"Jaudah let's go through the back just let's hurry" Mimi asked.
"Hey markonah, my car's in front" Denis said.
"Yaudah, you go with Denis, let me walk through the back" said Mimi.
"The guys just take the car, we're street girls. You know, we're kosan." said Muthia.
"Yaudah if so, we meet at the cost of Mimi if not meet on the road later." said Saridi.
The boys go to the front parking lot while Mimi and the others walk through the side gate to the boarding house.
Arriving at the boarding house they all enter the boarding house Mimi and Mimi put the place of the cake into the kitchen.
"Well, how nice is Mimi, ah why didn't I think of gini too?" said Irma.
"Yes Ma the same.. Eh Mi about kosan gini there is still an empty isn't it?" ask Muthia.
"Emm don't know if it's Muth, just try asking Retno's mother" said Mimi and gave ice syrup to all of them.
Yes Mimi and Bu Retno are familiar, even Miss Retno asked Mimi to call herself mother...
After resting for a while in the boarding house Mimi, they also began the road to the mall in this city.
Until the mall they went straight to one of the ice cream stand sellers and they all enjoyed the ice cream.
"Eh from here we go to the park or the square yok." invite Irma.
"Yes, bored ah in kosan mulu." said Selfia.
"Emm if you want to go, go.. Mimi didn't come" Mimi said
"Why Mi?" ask Muthia.
"It's what time you guys, Mimi has to make cake dough for tomorrow" said Mimi.
"Emmm, you don't" said Irma.
"Mi, tonight Thia can stay at Mimi's expense?" ask Muthia.
"Could it be Muth, what's wrong? usually if keg gini there is something." said Mimi.
"Hehee, please." said Muthia.
"Yaudah ntar stopped by kosan thia first to take a book MA dress for tomorrow" said Muthia to Dimas.
"Hemmm." replied Dimas.
"Muthia if you want to take a shower, take a shower first" Mimi told Muthia.
"Yes Mi, borrow a towel" he replied and borrowed a towel to Mimi, Mimi took a towel out of the closet and gave it to Muthia.
"Now" said Mimi.
"Thank you." Muthia answered and passed away going to the bathroom.
While Mimi fell down for a while while looking at her phone, it turns out so many chats came in from her friends in Jambi and no less chat from the idol.
While going to the mall, Mimi forgot to bring her cell phone in her college bag. Because I don't want there to be a misunderstanding Mimi also called heart adoration.
"Hallo assalamualaikum" said Mimi in front of the flat object.
Yes Mimi did a video call with Syahril.
"Waalaikum salam." replied Syahril ketus.
"Didih, ketusnya.." said Mimi again with a joke and smile but not with Syahril who put a sour face and glare sharp eyes.
"Sorry hehee" Mimi said again when she saw the face of the idol was like a starving lion.
"HP Mimi was left in the bag" Mimi said, explaining.
"Where was that!" said Syahril's turkey is still ketus.
"So college and there was an impromptu practicum continued to go home in the afternoon, continued to be invited friends to the mall" said Mimi.
"Hemm." he answered and Mimk just let out his breath.
"Yes earlier Fia and others. take a walk to the mall because they want refreshing he said because some of the full campus added there is impromptu practicum" explained Mimi.
"So what else, tumben in the room" said Mimi again.
"Once the prayer is over" he answered.
"Aren't you praying?" ask her.
"No." replied Mimi and Brother Syahril only linking his eyebrows together.
"It's a habit of arriving guests" Mimi said again.
"Ooo." said he.
"Oh yes deck, sister there is a surprise." he said.
"What?" ask Mimi.
"So my sister tried to apply for the final exam and has submitted her proposal thank God the proposal brother passed the deck" he said.
"Emm thank God, but that means what sis?" ask Mimk who doesn't understand.
"I mean the application for the sister's thesis submission at the agreed-in deck, and next month the sister exam and after that the trial script. Do'ain yank's brother to graduate quickly." he said.
"Amin, Alhamdulillah. May you pass your thesis and exam. Emm continued After that brother went on where?" mimi said and asked.
"Sister plans to continue on the LA deck, take the specialist" said Syahril.
"Well, far away." replied Mimi, somehow there was sadness on the day Mimi heard the idol would take his specialist in the land of people.
"Yes dek, sister again try to join the scholarship, hopefully graduate" he said with a happy hue.
"Amin" said Mimi.
"Hey how sad." said brother Syahril who saw softly on Mimi's face.
"Hmm if you pass the scholarship there, we rarely meet" said Mimi.
"God willing, if sister's holiday will meet adek. Or we marry and join brother to LA and continue his studies here." he said with a smile and played both eyebrows.
"Hmmm, dear money moved around" said Mimi.
"I don't know, Mimi wants to pursue Mimi's ideals from Mimi's hard work.. Mimi knows what oh brother would do for Mimi. But Mimk wants to pursue her in Mimi's way." Mimi explained.
"Dear, my brother knows only brother does not want to be adek always in bully there. Although I'm sure there must be someone who always protects the adek there" he said.
"Sister just wants us both, brother will protect adek from anyone." said Mr. Syahril.
"Mi.. where's the mukena?" ask Muthia who went into Mimi's room.
"That's Muth, take a new one in the study desk closet" Mimi replied by pointing to the study table.
"Who? Ayank beb huh?" muthia asked in a whisper and Mimi simply nodded.
"Upsss sorry.." she replied.
Continue on vc.
"Who's deck? Muthia?" ask Mr. Syahril.
"Yes, sister." replied Mimi.
"Oh he's staying in a dick?" ask Mr. Syahril.
"Yes, my dear" Mimi and Shahril replied, only nodding in understanding.
"Have you eaten?" ask Mimi.
"Not deck, what's cooking?" answer and ask again.
"Sweet sour spicy sauces" replied Mimi.
"Wah kangen brother, eat adek cuisine" he said.
"Hmmm here aja sak." said Muthia who had finished praying.
"They want." replied Brother Syahril.
"Sir Syahril has a single friend?" asked Muthia who was already beside Mimi.
"Why?" ask Mr. Syahril.
"If there is for Thia kak hehee." said Muthia.
"It was far from Muth's sword, there must be" replied Shahril.
"Hm... Wants like Mimi aja kak, can miss, if near bored hahaa.'' said Muthia.
"Where is Aceh Muth? " ask Syahril.
Yes Brother Syahril knows all about his friends Mimi because Mimi always tells the same story.
"Hmmm.. She.." said Muthia.
"Why?" ask Mimi.
"Hmm so, if there is a cariin for Muthia who is loyal like a sister" said Muthia.
"Feasily it depends on Muth's commitment, if there is no commitment with his partner is difficult. What else is LDR and." said Syahril.
"This is why a committed searchin is like a brother of Shahril" replied Muthia.
"Yes, I'll be looking for you." replied Brother Syahril.
"Thank you, brother, yaudah continued his kangen-kenan, Thia want to open the door first." he replied and left to go out of the room because someone knocked on the door.
"Who else is deck?" ask Mr. Syahril.
"Biasalah brother, Irma is with Fia." replied Mimi.
"Want to too?" ask Mr. Syahril.
"It's not known that those two people" Mimi replied.
"Emm yaudah, sister eat first yes.want to be accompanied by adek just not delicious with her friends." said Syahril.
"Okay sister, eat a lot ya.." replied Mimk with a smile.
"Don't forget the kiss yank" he said with a lip.
"Muaach, assalamualaikum." Mimi kissed the cell phone with Syahril's lips.
"Waalaikum greetings, do not forget to eat yank" he said.
"Yes, yes, brother, two rioters have entered" Mimi replied with !point the camera of his phone to the door.
"Yaudah, bye sweety" he said and immediately disconnected his phone call.
"Mana Mi,ayank bebnya." said Irma who immediately approached towards Mimi.
"Feed to eat." replied Mimi.
"Have you eaten yet?" mimi asked irma and Fia.
"Not yet Mi hehhee." replied irma and Fia.
"Jaudah, we eat yuk." replied Mimi and invited them all to eat.
Tonight not only Muthia who stayed at the boarding house Mimi, Fia and Irma also participated.
Tonight the three of them help Mimi make a cake for Mimi's merchandise tomorrow in the cafeteria, be a cake that is usually alone with shrewdness and this time rame-rame but according to Mimi instead takes a long time because making the cake interspersed with jokes and a lot of chatter that the beginning of the Muthia curse to the unfortunate chat.
tbc
